Description

1-Cyclopropyl-2-(2-Nitrophenyl)Ethanone is a specialized organic building block featuring a cyclopropyl ketone moiety adjacent to an ortho-nitrophenyl group. This unique molecular architecture makes it a valuable intermediate for synthesizing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the biological activity of the nitrophenyl and cyclopropyl motifs.
• Organic Synthesis Building Block: Serves as a versatile substrate for various reactions, including cyclizations, reductions, and cross-coupling, to create complex molecular libraries.
• Material Science: Potential intermediate for the synthesis of organic semiconductors, ligands for catalysts, and photoactive compounds.
• Academic & Contract Research: Essential for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1-Cyclopropyl-2-(2-Nitrophenyl)Ethanone
CAS No.	1178343-42-4
Molecular Formula	C11H11NO3
Molecular Weight	205.21 g/mol
Synonyms	2-(2-Nitrophenyl)-1-cyclopropylethanone; 1-Cyclopropyl-2-(2-nitrophenyl)ethan-1-one; 2-Nitrophenyl cyclopropyl ketone derivative; (2-Nitrophenyl)(cyclopropyl)methanone homologue; α-Cyclopropyl-2-nitroacetophenone; 2-(2-Nitrobenzyl)cyclopropanone (tautomeric form); NSC 1178343-42-4
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-2-(2-Nitrophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining it under an inert atmosphere such as nitrogen or argon to preserve stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.