Description

1-(4-Fluoro-3-Methylphenyl)Butan-1-Amine is a specialized aromatic amine building block featuring a fluorine substituent, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its unique structure contributes to enhanced metabolic stability and binding affinity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) agents, anti-inflammatory drugs, and kinase inhibitors.
• Agrochemical Research: Serves as a key precursor in the design and production of novel herbicides, fungicides, and insecticides, where the fluorine atom improves lipophilicity and environmental stability.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic amine functionality.
• Chemical Synthesis: Acts as a versatile amine reagent in organic synthesis for constructing complex molecules via amination, reductive amination, and coupling reactions.
• Bioconjugation & Probe Development: Employed in the creation of fluorescent probes, biomarkers, and bioconjugates for diagnostic and research applications.

Basic Information

Product Name	1-(4-Fluoro-3-Methylphenyl)Butan-1-Amine
CAS No.	1178100-82-7
Molecular Formula	C11H16FN
Molecular Weight	181.25 g/mol
Synonyms	1-(4-Fluoro-3-methylphenyl)butan-1-amine; 4-Fluoro-3-methylbenzenebutanamine; 1-Butylamine-4-fluoro-3-methylbenzene; 1-Aminobutyl-4-fluoro-3-methylbenzene; γ-(4-Fluoro-3-methylphenyl)butylamine; (4-Fluoro-3-methylphenyl)butylamine; 1-(4-Fluoro-3-methylphenyl)-1-butanamine
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-3-Methylphenyl)Butan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.