Description

(2-Piperazin-1-Ylpyrimidin-5-Yl)Boronic Acid is a high-purity boronic acid derivative and a valuable synthetic intermediate in modern organic chemistry. Its core value lies in its role as a key building block for constructing complex molecules via cross-coupling reactions, particularly Suzuki-Miyaura couplings. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymeric materials with specific functionalities.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based probes (ABPs) for target identification and validation.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel synthesis for high-throughput screening (HTS) campaigns.
• Ligand for Catalysis: Can be utilized to develop novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	(2-Piperazin-1-Ylpyrimidin-5-Yl)Boronic Acid
CAS No.	1176001-52-7
Molecular Formula	C8H13BN4O2
Molecular Weight	208.03 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperazin-1-yl)pyrimidine; 2-(Piperazin-1-yl)pyrimidine-5-boronic acid; 2-(1-Piperazinyl)-5-pyrimidineboronic acid; (2-(Piperazin-1-yl)pyrimidin-5-yl)boronic acid; B-[2-(1-Piperazinyl)-5-pyrimidinyl]boronic acid; 2-Piperazin-1-ylpyrimidine-5-boronic acid; (2-Piperazin-1-yl-5-pyrimidinyl)boronic acid
EINECS	Contact for details

Quality Control

Our (2-Piperazin-1-Ylpyrimidin-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.