Description

5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol is a fluorinated tetralin derivative, a high-value synthetic intermediate prized for its unique stereochemistry and fluorine atom. This compound is critical for introducing the 5-fluoro-1-tetralol pharmacophore into complex molecular architectures, enabling the development of novel bioactive compounds. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of advanced drug candidates, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, especially in CNS drug discovery.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex fluorinated organic molecules and studying structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation fluorinated pesticides and herbicides.
• Material Science: Potential intermediate for creating specialized fluorinated polymers or liquid crystals with unique electronic properties.
• Catalysis & Ligand Synthesis: Can be utilized to develop chiral ligands or catalysts for asymmetric synthesis applications.

Basic Information

Product Name	5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol
CAS No.	1175300-87-4
Molecular Formula	C₁₀H₁₁FO
Molecular Weight	166.19 g/mol
Synonyms	5-Fluoro-1-tetralol; 5-Fluoro-1,2,3,4-tetrahydro-1-naphthol; 1-Hydroxy-5-fluoro-1,2,3,4-tetrahydronaphthalene; 5-Fluoro-α-tetralol; (1RS)-5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-ol; 5-Fluoro-1,2,3,4-tetrahydro-1-naphthalenol; 5-Fluoro-1-hydroxy-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1,2,3,4-Tetrahydronaphthalen-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.