Description

Ethyl 1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine chemical class. This compound is a critical building block in modern medicinal chemistry, valued for its unique heterocyclic scaffold that enables the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Discovery: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies due to its privileged heterocyclic structure.
• CNS-Active Compound Synthesis: Utilized in developing candidates for neurological disorders, leveraging the physicochemical properties imparted by the pyrazolopyridine core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	1174844-27-9
Molecular Formula	C14H19N3O3
Molecular Weight	277.32 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6,7-dihydro-1-(1-methylethyl)-3-methyl-6-oxo-, ethyl ester; Ethyl 1-isopropyl-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate; 1-Isopropyl-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid ethyl ester; CAS 1174844-27-9; Fused Pyrazolopyridine Derivative; Pyrazolopyridine Ester Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for analytical method validation where applicable, ensuring data integrity and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Store away from incompatible materials such as strong bases and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.