Description

1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Ethanone is a high-value, protected boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in constructing heterocyclic cores prevalent in modern therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides that require specific boronic acid ester functionalities.
• Material Science Research: Employed in the development of organic electronic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors for biological target studies.
• Catalyst & Ligand Development: Serves as a precursor for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Ethanone
CAS No.	1174718-91-2
Molecular Formula	C12H20BNO3
Molecular Weight	237.11 g/mol
Synonyms	1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrol-1-yl]ethanone; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrol-1-yl)ethan-1-one; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-acetate; 1-Acetyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 3-Pinacolatoboryl-1-acetylpyrrole; 1-Acetyl-3-pinacolatoborylpyrrole; 3-(Pinacolatoboryl)-1-acetyl-1H-pyrrole
EINECS	Contact for details

Quality Control

Our production of 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive cross-coupling reactions. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ISO 9001 quality standards and can provide material suitable for research and development under current Good Manufacturing Practice (cGMP) guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.