Description

[4-(1H-Pyrazol-5-Yl)Phenyl]Boronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its ability to form carbon-carbon bonds to create complex bioactive structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and molecular components for OLEDs and sensors.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and affinity ligands.
• Catalyst & Ligand Development: Serves as a starting material for creating novel bidentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital raw material for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	[4-(1H-Pyrazol-5-Yl)Phenyl]Boronic Acid
CAS No.	1174304-73-4
Molecular Formula	C9H9BN2O2
Molecular Weight	188.00 g/mol
Synonyms	5-(4-Boronophenyl)-1H-pyrazole; [4-(1H-Pyrazol-5-yl)phenyl]boronic acid; 4-(1H-Pyrazol-5-yl)benzeneboronic acid; (4-(1H-Pyrazol-5-yl)phenyl)boronic acid; B-[4-(1H-Pyrazol-5-yl)phenyl]boronic acid; 4-(1H-Pyrazol-5-yl)phenylboronic acid; 4-(1H-Pyrazol-5-yl)benzeneboronic acid; 4-(1H-Pyrazol-5-yl)phenylboronic acid pinacol ester (protected form)
EINECS	Contact for details

Quality Control

Our [4-(1H-Pyrazol-5-Yl)Phenyl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive applications like pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.