Description

4-(1-Hydroxyethyl)Benzeneboronic acid, Pinacol ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex biaryl and heterobiaryl scaffolds for active ingredient development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical suppliers performing bespoke synthesis.

Basic Information

Product Name	4-(1-Hydroxyethyl)Benzeneboronic acid, Pinacol ester
CAS No.	1173922-30-9
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	[4-(1-Hydroxyethyl)phenyl]boronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanol; 4-(1-Hydroxyethyl)phenylboronic acid pinacol ester; 2-[4-(1-Hydroxyethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol [4-(1-hydroxyethyl)phenyl]boronate; 4-(1-Hydroxyethyl)benzeneboronic acid pinanediol ester (common alternative protection); B-[4-(1-Hydroxyethyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(1-Hydroxyethyl)Benzeneboronic acid, Pinacol ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.