Description

Enrofloxacin-D5 is a deuterium-labeled internal standard of the broad-spectrum fluoroquinolone antibiotic, Enrofloxacin, essential for ensuring accuracy and reliability in quantitative analytical methods. This high-purity stable isotope-labeled compound is critical for researchers and quality control laboratories requiring precise measurement and validation in complex matrices. It is primarily used in the pharmaceutical, veterinary medicine, and food safety sectors for advanced mass spectrometry-based applications such as pharmacokinetic studies, residue testing, and method development.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate determination of Enrofloxacin residues.
• Veterinary Drug Residue Analysis: Critical for testing meat, milk, eggs, and honey to ensure compliance with maximum residue limits (MRLs) and food safety regulations.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking and quantification of Enrofloxacin and its metabolites in biological fluids and tissues during drug development.
• Method Development and Validation: Serves as a key component in establishing and validating robust analytical methods in regulatory and research laboratories.
• Quality Control in Pharmaceutical Manufacturing: Used in the quality assurance processes for the production of Enrofloxacin and related pharmaceutical formulations.
• Environmental Monitoring: Applied in the analysis of water and soil samples for veterinary antibiotic contamination studies.

Basic Information

Product Name	Enrofloxacin-D5
CAS No.	1173021-92-5
Molecular Formula	C19H17D5FN3O3
Molecular Weight	363.40 g/mol
Synonyms	1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-D5; Baytril-D5; Ethylciprofloxacin-D5; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid-D5; Enrofloxacin (phenyl-D5); Enrofloxacin-d5; Enrofloxacin (ethyl-d5)
EINECS	Contact for details

Quality Control

Our Enrofloxacin-D5 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity (by HPLC), and residual solvent content. We support compliance with GMP and ISO 17025 standards for reference materials, and COAs are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.