Description

Febantel D6 is a deuterated analog of the anthelmintic drug Febantel, serving as a critical internal standard for precise quantitative analysis in mass spectrometry. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in pharmacokinetic and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in veterinary drug development and residue analysis.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard for the accurate quantification of Febantel and its metabolites in complex biological matrices.
• Veterinary Pharmaceutical Research: Facilitates pharmacokinetic (PK) and bioavailability studies in the development of new anthelmintic formulations.
• Metabolite Identification: Aids in the structural elucidation and tracking of drug metabolites during in vitro and in vivo metabolism studies.
• Residue Analysis: Critical for regulatory compliance testing, ensuring accurate measurement of drug residues in food-producing animals and animal-derived products.
• Method Development and Validation: Employed to develop, optimize, and validate robust analytical methods in compliance with Good Laboratory Practice (GLP) and ICH guidelines.
• Quality Control in Manufacturing: Supports the quality assurance of active pharmaceutical ingredients (APIs) and finished drug products through high-precision analytical techniques.

Basic Information

Product Name	Febantel D6
CAS No.	1173021-79-8
Molecular Formula	C20H17D6N3O6S
Molecular Weight	447.51 g/mol
Synonyms	Febantel-d6; [D6]-Febantel; 2-[(Methoxy-D3)carbonyl]-N-[5-(propylsulfanyl-D3)-1H-benzimidazol-2-yl]carbamic acid phenylmethyl ester; Methyl [5-(propylsulfanyl-D3)-1H-benzimidazol-2-yl]carbamate 4,4'-bis(phenylmethyl) ester-d6; (RS)-Febantel-d6; Deuterated Febantel
EINECS	Contact for details

Quality Control

Our Febantel D6 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch undergoes comprehensive testing, including HPLC for chemical purity, NMR and MS for isotopic enrichment and positional verification, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for use as an internal standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.