Description

5-(Methothio)Thiophene-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex sulfur-containing heterocyclic scaffolds. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its stability as a pinacol ester makes it a reliable reagent for demanding synthesis protocols.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing thiophene and thioether motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific sulfur-heterocycle structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as conductive polymers, OLEDs, and organic semiconductors, where thiophene derivatives are fundamental.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	5-(Methothio)Thiophene-2-Boronic Acid Pinacol Ester
CAS No.	1172999-13-1
Molecular Formula	C11H17BO2S2
Molecular Weight	256.19 g/mol
Synonyms	5-(Methylthio)thiophene-2-boronic acid pinacol ester; 2-(5-Methylthiothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methylsulfanylthiophene-2-boronic acid pinacol ester; 5-(Methylsulfanyl)thiophene-2-boronic acid pinacol ester; 5-(Methylmercapto)thiophene-2-boronic acid pinacol ester; 5-(Methothio)thiophene-2-boronic acid neopentyl glycol ester (common alternative); 5-MTTA-PE (abbreviation)
EINECS	Contact for details

Quality Control

Our 5-(Methothio)Thiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the consistency and reliability required for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.