Description

Acetamide, n-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, organoboron-containing acetamide derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in the 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (pinacol boronate ester) functional group, which enables efficient cross-coupling reactions for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key structural motifs in active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other small-molecule therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester group makes it an ideal partner for palladium-catalyzed cross-coupling with aryl/heteroaryl halides, a cornerstone reaction in medicinal and process chemistry.
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides, where the acetamide moiety and aryl-boronate functionality are valuable structural components.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Can be utilized as a probe or linker in bioconjugation strategies and the development of chemical tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Acetamide, n-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	1172115-34-2
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylphenyl]acetamide; 3'-Acetamido-4'-methylphenylboronic acid pinacol ester; (3-Acetamido-4-methylphenyl)boronic acid pinacol ester; N-(4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide; Acetamide, N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 1172115-34-2; Boronic acid, B-[3-(acetylamino)-4-methylphenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Acetamide, n-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.