Description

3-(1-Methyl-1H-Pyrazol-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex molecular architectures. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological research.
• Catalyst & Ligand Development: Utilized to construct novel bidentate or tridentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a pyridine-pyrazole pharmacophore.

Basic Information

Product Name	3-(1-Methyl-1H-Pyrazol-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1171892-77-5
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(1-methyl-1H-pyrazol-4-yl)pyridine; 3-(1-Methyl-1H-pyrazol-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 3-(1-methyl-1H-pyrazol-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1171892-77-5; 3-Pyridinylboronic acid, 5-(1-methyl-1H-pyrazol-4-yl)-, pinacol ester; Boronic acid, B-[5-(1-methyl-1H-pyrazol-4-yl)-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-(1-Methyl-1H-Pyrazol-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. All materials are characterized by advanced analytical techniques including NMR (1H, 13C, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage or after opening to maintain stability and reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.