Description

3-Ethoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in the pyridine-boronic ester moiety, which is essential for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds between the pyridine ring and various aryl or vinyl halides, enabling the construction of complex biaryl structures.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysts or as a component in metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Acts as a starting point for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	3-Ethoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1171892-40-2
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-ethoxypyridine; 3-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Ethoxypyridine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-ethoxy-pyridine; Pyridine, 3-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Ethoxy-5-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.