Description

5-(Methylthio)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and biochemical tools for studying biological processes.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds under mild conditions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Methylthio)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1171891-40-9
Molecular Formula	C₁₃H₂₀BNO₂S
Molecular Weight	265.18 g/mol
Synonyms	5-(Methylthio)-3-pyridineboronic acid pinacol ester; 3-Borono-5-(methylthio)pyridine pinacol ester; [5-(Methylsulfanyl)pyridin-3-yl]boronic acid pinacol ester; 5-(Methylmercapto)pyridine-3-boronic acid pinacol ester; Pinacol [5-(methylthio)pyridin-3-yl]boronate; 5-Methylthiopyridine-3-boronic acid pinacol ester; CAS 1171891-40-9
EINECS	Contact for details

Quality Control

Every batch of 5-(Methylthio)Pyridine-3-Boronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are aligned with industry best practices for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.