Description

3-Dimethylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Propionamide is a high-value, functionalized pyridine-boronic ester derivative designed for advanced synthetic chemistry. This compound matters as a critical building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing pyridine and biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds with aryl/heteroaryl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers where precise molecular structure is critical.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tools to study biological processes.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	3-Dimethylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Propionamide
CAS No.	1171891-23-8
Molecular Formula	C18H30BN3O3
Molecular Weight	347.26 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[3-(dimethylamino)propyl]nicotinamide; 3-Dimethylamino-N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]propanamide; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-(dimethylamino)propyl)pyridine-3-carboxamide; N-(3-(Dimethylamino)propyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinamide; 1171891-23-8; Boronic ester pyridine derivative; Pinacol boronate pyridine amide
EINECS	Contact for details

Quality Control

Our 3-Dimethylamino-n-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Yl]Propionamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic and moisture-sensitive; keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.