Description

3-(4-Methoxyphenyl)-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for developing new active compounds. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers specializing in custom synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biphenyl or heterobiaryl motifs.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products, leveraging its boronic ester functionality for structural diversification.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or components for organic semiconductors.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies offering bespoke synthesis services.

Basic Information

Product Name	3-(4-Methoxyphenyl)-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	1171891-09-0
Molecular Formula	C19H24BNO3
Molecular Weight	325.21 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(4-methoxyphenyl)pyridine; 3-(4-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(p-Methoxyphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1171891-09-0; 3-(4-Methoxyphenyl)pyridin-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3-(4-methoxyphenyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxyphenyl)-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research and cGMP-grade material for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation of the boronic ester functionality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.