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5-Phenyl-3-Pyridinyl Boronic Acid, Pinacol Ester CAS NO 1171891-07-8


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CAS No.:1171891-07-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Phenyl-3-Pyridinyl Boronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is crucial as a key building block in modern cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for forming carbon-carbon bonds between the pyridinyl moiety and various aryl/heteroaryl halides.
  • Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or heterobiaryl scaffolds.
  • Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and insecticides with complex aromatic systems.
  • Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Material Science: Used in the development of organic electronic materials, such as those for OLEDs and semiconductors.
  • Chemical Biology & Probe Development: Facilitates the creation of molecular probes and labeled compounds for biological target identification.

Basic Information

Product Name 5-Phenyl-3-Pyridinyl Boronic Acid, Pinacol Ester
CAS No. 1171891-07-8
Molecular Formula C17H20BNO2
Molecular Weight 281.16 g/mol
Synonyms 5-Phenyl-3-pyridinylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-phenylpyridine; 5-Phenyl-3-pyridylboronic acid pinacol ester; 5-Phenylpyridin-3-ylboronic acid pinacol ester; 2-(5-Phenylpyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Pyridinylboronic acid, 5-phenyl-, pinacol ester; Boronic acid, B-(5-phenyl-3-pyridinyl)-, 1,1-dimethylethyl ester
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Quality Control

Our 5-Phenyl-3-Pyridinyl Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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