Description

2-Chloro-5-Trifluoromethyl-Benzamidine Hydrochloride is a high-purity, halogenated benzamidine derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmacological building block and intermediate for the development of novel active ingredients. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating new molecular entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of protease inhibitors and other small-molecule drug candidates targeting various diseases.
• Agrochemical Research: Used in developing new herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Chemical Biology Probe: Serves as a scaffold for designing enzyme inhibitors and molecular probes to study biological pathways.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and heterocycle formation due to its reactive amidine and chloro functionalities.
• Material Science Research: Potential intermediate for synthesizing specialty polymers and advanced materials with specific electronic properties.

Basic Information

Product Name	2-Chloro-5-Trifluoromethyl-Benzamidine Hydrochloride
CAS No.	1171628-53-7
Molecular Formula	C8H7ClF3N2•HCl
Molecular Weight	261.51 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)benzamidine hydrochloride; 2-Chloro-α,α,α-trifluoro-p-toluamidine hydrochloride; Benzenecarboximidamide, 2-chloro-5-(trifluoromethyl)-, hydrochloride (1:1); 2-Chloro-5-trifluoromethylbenzamidine HCl; 2-Chloro-5-trifluoromethylbenzenecarboximidamide hydrochloride; (2-Chloro-5-(trifluoromethyl)phenyl)methanimidamide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Trifluoromethyl-Benzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.