Description

(3-((4-Methylpiperazin-1-yl)methyl)phenyl)boronic acid is a high-value, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a methylpiperazine moiety that offers enhanced solubility and pharmacological relevance. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require advanced intermediates for the development of novel active ingredients. Its precise structure enables the efficient synthesis of complex molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds in medicinal chemistry and materials science research.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that require complex, nitrogen-containing heterocycles.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Intermediate for creating organic electronic materials and advanced polymers with tailored properties.

Basic Information

Product Name	(3-((4-Methylpiperazin-1-yl)methyl)phenyl)boronic Acid
CAS No.	1171044-16-8
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	[3-[(4-Methyl-1-piperazinyl)methyl]phenyl]boronic acid; (3-((4-Methylpiperazin-1-yl)methyl)phenyl)boronic acid pinacol ester (protected form); 3-[(4-Methylpiperazin-1-yl)methyl]benzeneboronic acid; B-[3-[(4-Methyl-1-piperazinyl)methyl]phenyl]boronic acid; 1171044-16-8; Boronic acid, B-[3-[(4-methyl-1-piperazinyl)methyl]phenyl]-; 3-(4-Methylpiperazin-1-ylmethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our (3-((4-Methylpiperazin-1-yl)methyl)phenyl)boronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.