Description

4-Hydrazino-6-Trifluoromethylquinoline Hydrochloride is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydrazino group and a trifluoromethyl substituent, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Building block for creating specialized organic ligands, dyes, or functional polymers with specific electronic properties.
• Chemical Synthesis: Versatile reagent for introducing the hydrazino-quinoline scaffold into more complex molecular architectures via condensation or cyclization reactions.
• Academic & Contract Research: Essential material for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Hydrazino-6-Trifluoromethylquinoline Hydrochloride
CAS No.	1170816-62-2
Molecular Formula	C₁₀H₈F₃N₃·HCl
Molecular Weight	263.65 g/mol (Free base)
Synonyms	6-(Trifluoromethyl)-4-quinolinehydrazine hydrochloride; 4-Hydrazinyl-6-(trifluoromethyl)quinoline hydrochloride; 4-Hydrazino-6-trifluoromethylquinoline HCl; 6-Trifluoromethyl-4-hydrazinoquinoline hydrochloride; Quinoline, 4-hydrazino-6-(trifluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Hydrazino-6-Trifluoromethylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.