Description

(3-(2-(4-Methylpiperazin-1-Yl)Ethoxy)Phenyl)Boronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a piperazine moiety that offers excellent solubility and potential for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to create biaryl structures, a fundamental reaction in medicinal chemistry and material science.
• Protecting Group & Derivatization: The boronic acid group can act as a protecting group or be further functionalized, while the piperazine ring allows for the introduction of diverse pharmacophores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific aryl-piperazine motifs.
• Ligand for Catalysis: Can be utilized to develop novel ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors and light-emitting materials for electronic devices.

Basic Information

Product Name	(3-(2-(4-Methylpiperazin-1-Yl)Ethoxy)Phenyl)Boronic Acid
CAS No.	1170697-43-4
Molecular Formula	C13H21BN2O3
Molecular Weight	264.13 g/mol
Synonyms	[3-[2-(4-Methyl-1-piperazinyl)ethoxy]phenyl]boronic acid; 3-[2-(4-Methylpiperazin-1-yl)ethoxy]benzeneboronic acid; (3-(2-(4-Methylpiperazin-1-yl)ethoxy)phenyl)boronic acid; B-[3-[2-(4-Methyl-1-piperazinyl)ethoxy]phenyl]-boronic acid; 1170697-43-4; (3-(2-(4-Methylpiperazin-1-yl)ethoxy)phenyl)boronic acid pinacol ester (related protected form)
EINECS	Contact for details

Quality Control

Our (3-(2-(4-Methylpiperazin-1-Yl)Ethoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.