Description

2-Phenyl-1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-1H-Benzoimidazole is a high-value, synthetically versatile boronic ester derivative, serving as a critical advanced pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent. Its molecular architecture, featuring a benzimidazole core linked to a pinacol boronate ester, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, handleable aryl boronate ester partner for forming carbon-carbon bonds in complex molecule assembly.
• Organic Light-Emitting Diode (OLED) Materials Research: Used in the development of electron-transporting or host materials due to the benzimidazole moiety.
• Ligand Synthesis for Catalysis: Precursor for creating sophisticated nitrogen-containing ligands used in homogeneous catalysis.
• Agrochemical Intermediate: Employed in the research and development of new generation crop protection agents with complex heterocyclic structures.
• Material Science: Building block for functional polymers and advanced organic frameworks with tailored electronic properties.

Basic Information

Product Name	2-Phenyl-1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-1H-Benzoimidazole
CAS No.	1169709-19-6
Molecular Formula	C25H25BN2O2
Molecular Weight	396.29 g/mol
Synonyms	2-Phenyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-benzimidazole; 1H-Benzimidazole, 2-phenyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 4-(2-Phenyl-1H-benzimidazol-1-yl)phenylboronic acid pinacol ester; [4-(2-Phenyl-1H-benzoimidazol-1-yl)phenyl]boronic acid pinacol ester; 2-Phenyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-benzo[d]imidazole; Benzimidazole Boronic Ester Pinacol; 1169709-19-6
EINECS	Contact for details

Quality Control

Every batch of our 2-Phenyl-1-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-1H-Benzoimidazole is manufactured under strict quality management systems. We guarantee high purity and batch-to-batch consistency through comprehensive analytical testing, including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.