Description

Pyrazolo[1,5-A]Pyrimidine-3-Boronic Acid Pinacol Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in kinase inhibitor and heterocyclic compound libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: Enables the precise construction of complex, functionalized pyrazolopyrimidine scaffolds for further chemical exploration.
• Bioconjugation & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for diagnostic and biochemical research.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Boronic Acid Pinacol Ester
CAS No.	1169690-88-3
Molecular Formula	C₁₃H₁₈BN₃O₂
Molecular Weight	259.11 g/mol
Synonyms	Pyrazolo[1,5-a]pyrimidin-3-ylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine-3-boronic acid pinacol ester; 1169690-88-3; B-(Pyrazolo[1,5-a]pyrimidin-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine-3-boronic acid, pinacol ester.
EINECS	Contact for details

Quality Control

Every batch of Pyrazolo[1,5-A]Pyrimidine-3-Boronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive coupling reactions. Our quality commitment includes comprehensive analysis via HPLC, NMR (¹H and ¹³C), and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.