Description

Ethyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyridine-2-Carboxylate is a high-value imidazopyridine boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED emitters and charge transport layers.
• Chemical Biology Probes: Enables the creation of tagged molecules for studying biological pathways and target engagement.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry.
• Academic & Contract Research: A critical reagent for methodology development and complex molecule synthesis in academic and CRO laboratories.

Basic Information

Product Name	Ethyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	1168208-51-2
Molecular Formula	C18H23BN2O4
Molecular Weight	342.20 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Ethyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine-2-carboxylate; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; 6-Pinacolatoborylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; 1168208-51-2; Ethyl 6-Boronimidazo[1,2-a]pyridine-2-carboxylate pinacol ester.
EINECS	Contact for details

Quality Control

Our Ethyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Imidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere if possible to maximize long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.