Description

6-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Amine is a high-purity, heterocyclic aromatic amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel crop protection agents and herbicides.
• Biochemical Tool Compound: Utilized in the development of probes and assay reagents for biological target validation.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	6-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Amine
CAS No.	1167608-96-9
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	6-Chloro-3-amino-1H-pyrrolo[2,3-b]pyridine; 3-Amino-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridin-3-amine; 6-Chloro-3-pyrrolo[2,3-b]pyridinamine; 6-Chloro-1H-pyrrolo[2,3-b]pyridin-3-ylamine; 6-Chloro-7-azaindol-3-amine; 6-Chloro-3-amino-7-azaindole
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.