Description

2-(1,3-Dioxolan-2-Yl)-1-(4-Fluoro-Phenyl)-Ethanone is a high-purity organic building block featuring a protected carbonyl group and a fluorinated aromatic ring. This compound is valued for its role as a versatile synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability and reactivity of the dioxolane-protected ketone.
• Material Science Research: Serves as a precursor for creating specialized polymers and liquid crystals where the fluorine moiety imparts desired physical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex heterocycles and as a substrate in catalytic cross-coupling reactions.
• Fine Chemical Production: Integral in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-(1,3-Dioxolan-2-Yl)-1-(4-Fluoro-Phenyl)-Ethanone
CAS No.	1166996-38-8
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	1-(4-Fluorophenyl)-2-(1,3-dioxolan-2-yl)ethanone; 2-(1,3-Dioxolan-2-yl)-1-(4-fluorophenyl)ethanone; 4'-Fluoro-2-(1,3-dioxolan-2-yl)acetophenone; 1-(4-Fluorophenyl)-2-(1,3-dioxolan-2-yl)ethan-1-one; 2-(1,3-Dioxolan-2-yl)-1-(4-fluorophenyl)ethan-1-one; 4-Fluorophenyl 2-(1,3-dioxolan-2-yl) ketone
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dioxolan-2-Yl)-1-(4-Fluoro-Phenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and other relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.