Description

1-(4-Fluorophenyl)-2-(Oxolan-2-Yl)Ethan-1-One is a high-purity fluorinated organic building block characterized by its unique molecular architecture combining a fluorophenyl group with a tetrahydrofuran-derived ketone. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for methodological studies, including asymmetric synthesis and cross-coupling reactions.
• Ligand and Catalyst Development: Useful scaffold for creating novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	1-(4-Fluorophenyl)-2-(Oxolan-2-Yl)Ethan-1-One
CAS No.	1166996-25-3
Molecular Formula	C12H13FO2
Molecular Weight	208.23 g/mol
Synonyms	2-(4-Fluorophenyl)-1-(Tetrahydrofuran-2-yl)ethanone; 1-(4-Fluorophenyl)-2-(Tetrahydrofuran-2-yl)ethan-1-one; 4-Fluoro-α-(tetrahydro-2-furanyl)acetophenone; 2-(4-Fluorobenzoyl)methyltetrahydrofuran; (4-Fluorophenyl)(tetrahydrofuran-2-yl)methyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-2-(Oxolan-2-Yl)Ethan-1-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.