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4,4,5,5-Tetramethyl-2-(2,3,4-Trichlorophenyl)-1,3,2-Dioxaborolane CAS NO 1165935-95-4


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CAS No.:1165935-95-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4,4,5,5-Tetramethyl-2-(2,3,4-Trichlorophenyl)-1,3,2-Dioxaborolane is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical Suzuki-Miyaura cross-coupling reagent, enabling the efficient formation of carbon-carbon bonds in complex molecule assembly. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel compounds and intermediates.

Application

  • Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl scaffolds in active pharmaceutical ingredient (API) development.
  • Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides with complex aromatic structures.
  • Material Science: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
  • Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of probe molecules and labeled compounds for biological target identification and validation.
  • Catalyst & Ligand Development: Acts as a precursor for novel catalysts and ligands used in asymmetric synthesis and other catalytic processes.
  • Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the global fine chemical market.

Basic Information

Item Details
Product Name 4,4,5,5-Tetramethyl-2-(2,3,4-Trichlorophenyl)-1,3,2-Dioxaborolane
CAS No. 1165935-95-4
Molecular Formula C12H14BCl3O2
Molecular Weight 313.41 g/mol
Synonyms 2-(2,3,4-Trichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2,3,4-Trichlorophenyl)boronic acid pinacol ester; 2,3,4-Trichlorophenylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2,3,4-trichlorophenyl)-1,3,2-dioxaborolane; (2,3,4-Trichlorophenyl)BPin; 2,3,4-TrichlorophenylBPin; 2,3,4-Trichlorophenyl Pinacol Boronate
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Quality Control

Our 4,4,5,5-Tetramethyl-2-(2,3,4-Trichlorophenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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