Description

4,4,5,5-Tetramethyl-2-(2,4,5-Trichlorophenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure enables key carbon-carbon bond-forming reactions. It is primarily utilized by research scientists and process chemists in the development of active pharmaceutical ingredients (APIs), functional materials, and novel crop protection agents.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in pharmaceutical intermediates.
• Pharmaceutical Research & Development: Serves as a versatile building block for synthesizing potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: A precursor for organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Catalyst and Ligand Development: Used to synthesize novel ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2,4,5-Trichlorophenyl)-1,3,2-Dioxaborolane
CAS No.	1165935-93-2
Molecular Formula	C12H14BCl3O2
Molecular Weight	313.41 g/mol
Synonyms	2-(2,4,5-Trichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2,4,5-Trichlorophenyl)boronic acid pinacol ester; 2,4,5-Trichlorophenylboronic acid pinacol ester; Pinacol (2,4,5-trichlorophenyl)boronate; 4,4,5,5-Tetramethyl-2-(2,4,5-trichlorophenyl)-1,3,2-dioxaborolane; 2,4,5-TrichlorophenylBPin; TCPh-BPin
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2,4,5-Trichlorophenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including NMR, HPLC, and GC analysis, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.