Description

6-Chloropyridazine-3-Boronic Acid Pinacol Ester is a high-value, heterocyclic boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing pyridazine-based drug candidates in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: The protected boronic acid functionality is specifically designed for palladium-catalyzed carbon-carbon bond formation under mild conditions.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biological target identification.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Chloropyridazine-3-Boronic Acid Pinacol Ester
CAS No.	1162261-98-4
Molecular Formula	C11H14BClN2O2
Molecular Weight	252.50 g/mol
Synonyms	6-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine; 6-Chloropyridazine-3-boronic acid pinacol ester; 2-(6-Chloropyridazin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Chloro-3-pyridazineboronic acid pinacol ester; 3-Boronic acid, 6-chloropyridazine-, pinacol ester; (6-Chloropyridazin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Chloropyridazine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.