Description

Chloro(Mesitylene)[(1R,2R)-(-)-2-Amino-1,2-Diphenylethyl(Methylsulfonylamido)]Ruthenium(II) RuCl(Mesitylene)[(R,R)-MsDPEN] is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters as a premier catalyst for enantioselective hydrogenation and transfer hydrogenation reactions, enabling the production of single-enantiomer intermediates with high optical purity. It is critically needed by pharmaceutical R&D laboratories and fine chemical manufacturers for synthesizing chiral amines and amino alcohols, which are key building blocks for active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: In the production of chiral building blocks for APIs, including β-amino alcohols and derivatives.
• Transfer Hydrogenation Reactions: Utilizing hydrogen donors like formic acid or isopropanol for selective reductions under mild conditions.
• Academic & Industrial R&D: As a key reagent for developing new synthetic methodologies in asymmetric synthesis.
• Fine Chemical Manufacturing: For the scalable, stereoselective synthesis of high-value specialty chemicals.
• Chiral Ligand Precursor: Serving as a source of the (R,R)-MsDPEN ligand framework for other metal complexes.

Basic Information

Product Name	Chloro(Mesitylene)[(1R,2R)-(-)-2-Amino-1,2-Diphenylethyl(Methylsulfonylamido)]Ruthenium(II)
CAS No.	1160707-20-9
Molecular Formula	C24H29ClN2O2RuS
Molecular Weight	546.08 g/mol
Synonyms	RuCl(R,R)-MsDPEN; (R,R)-RuCl(mesitylene)(MsDPEN); N-((1R,2R)-2-(Methylsulfonamido)-1,2-diphenylethyl)arenesulfonamidoruthenium complex; Chiral Ruthenium-MsDPEN Catalyst; [RuCl(mesitylene)((R,R)-MsDPEN)]; Asymmetric Hydrogenation Catalyst Ru-MsDPEN; (R,R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium Complex; RuCl(TsDPEN)(p-cymene) analog
EINECS	Contact for details

Quality Control

Our Chloro(Mesitylene)[(R,R)-MsDPEN]Ruthenium(II) catalyst is produced under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific performance characteristics is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and decomposition. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Ruthenium Content (ICP-OES)	18.0 - 20.0 %
Solubility	Soluble in dichloromethane, toluene; slightly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.