Description

1-Bromo-2-Chloro-3,4-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced chemical synthesis. Its precise halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for fluorine-containing drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoro motif enhances bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display and lighting applications.
• Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce halogenated aromatic units into high-performance polymers.
• Organic Synthesis & Catalysis: Acts as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalyst design.
• Material Science Research: Utilized in the creation of novel organic semiconductors and other functional materials due to its electron-withdrawing characteristics.

Basic Information

Item	Detail
Product Name	1-Bromo-2-Chloro-3,4-Difluorobenzene
CAS No.	1160574-70-8
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2-Bromo-1-Chloro-3,4-Difluorobenzene; 3,4-Difluoro-2-bromo-1-chlorobenzene; 1-Chloro-2-bromo-3,4-difluorobenzene; Benzene, 1-bromo-2-chloro-3,4-difluoro-; 2-Chloro-1-bromo-3,4-difluorobenzene; 3,4-Difluoro-1-bromo-2-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3,4-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.