Description

1-Bromo-2-Chloro-5-Fluoro-4-Iodobenzene is a highly functionalized, multi-halogenated benzene derivative that serves as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an invaluable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides with specific halogenated aromatic cores.
• Material Science Research: Building block for creating organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromine and iodine substituents.
• Ligand and Catalyst Development: Used to synthesize novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Employed in the creation of fluorescent tags and molecular probes for biochemical research.

Basic Information

Product Name	1-Bromo-2-Chloro-5-Fluoro-4-Iodobenzene
CAS No.	1160574-56-0
Molecular Formula	C6H2BrClFI
Molecular Weight	335.34 g/mol
Synonyms	2-Bromo-1-Chloro-4-Fluoro-5-Iodobenzene; 4-Bromo-3-Chloro-6-Fluoroidobenzene; Benzene, 1-bromo-2-chloro-5-fluoro-4-iodo-; BCFI-Benzene; 1-Bromo-2-chloro-5-fluoro-4-iodo-benzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-5-Fluoro-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.