Description

2-Bromo-5-Chloroethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromo and chloro substituents on an ethylbenzene core, makes it a versatile precursor for constructing complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce specific halogenated aromatic motifs into target compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic rings for bioactivity or as handles for further functionalization.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the halogen atoms can be pivotal for efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystals and organic light-emitting diodes (OLEDs), due to its rigid, substituted benzene structure.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) where the bromine atom acts as a superior leaving group compared to chlorine.
• Polymer Modification: Employed to introduce halogenated aromatic side chains into polymers, altering their physical properties such as flame retardancy, refractive index, or solubility.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	2-Bromo-5-Chloroethylbenzene
CAS No.	1160573-89-6
Molecular Formula	C8H8BrCl
Molecular Weight	219.51 g/mol
Synonyms	1-Bromo-4-chloro-2-ethylbenzene; 2-Ethyl-1-bromo-4-chlorobenzene; 4-Chloro-2-ethyl-1-bromobenzene; 2-Bromo-5-chloro-1-ethylbenzene; (2-Bromo-5-chlorophenyl)ethane; 2-Bromo-5-chloroethylbenzene; 2-Bromo-5-chloroethylbenzene (CAS 1160573-89-6)
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloroethylbenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to a cGMP-compliant quality management system, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is between 2°C and 8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/GC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.