Description

1-Bromo-2-Ethyl-4-Iodobenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring complex halogenated aromatic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the ethyl and halogen substituents modulate biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings, leveraging both the bromo and iodo functional groups for sequential functionalization.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal complexes used in catalysis.
• Chemical Biology Probes: Useful for incorporating halogen tags into molecules for imaging, binding studies, or as mechanistic probes.

Basic Information

Item	Details
Product Name	1-Bromo-2-Ethyl-4-Iodobenzene
CAS No.	1160573-87-4
Molecular Formula	C8H8BrI
Molecular Weight	310.96 g/mol
Synonyms	2-Ethyl-1-bromo-4-iodobenzene; 4-Bromo-3-ethyl-1-iodobenzene; 1-Bromo-2-ethyl-4-iodo-benzene; 2-Ethyl-4-iodobromobenzene; 4-Iodo-2-ethylbromobenzene; (2-Ethyl-4-iodophenyl)bromide; Benzene, 1-bromo-2-ethyl-4-iodo-
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Ethyl-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to ensure full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.