Description

1-Bromo-3-Chloro-2,5-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorine-containing drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides where the halogen pattern influences bioactivity.
• Material Science: Used in the research and production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing complex functionalities.
• Ligand and Catalyst Development: Serves as a scaffold for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	1-Bromo-3-Chloro-2,5-Difluorobenzene
CAS No.	1160573-67-0
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2,5-Difluoro-1-bromo-3-chlorobenzene; 3-Bromo-1-chloro-2,5-difluorobenzene; Benzene, 1-bromo-3-chloro-2,5-difluoro-; 1-Bromo-3-chloro-2,5-difluorobenzene; 2,5-Difluoro-3-bromo-1-chlorobenzene; 3-Chloro-1-bromo-2,5-difluorobenzene; B3CDFB (abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-2,5-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.