Description

1-Bromo-2-Iodo-3-Methyl-5-Nitrobenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used in the synthesis of advanced pesticide and herbicide molecules, leveraging its halogen atoms for structural diversity.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and charge-transport molecules.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Heck) due to the presence of both bromine and iodine leaving groups with different reactivities.
• Ligand and Catalyst Development: Used to create sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized nitro-aromatic dyes and colorants.

Basic Information

Product Name	1-Bromo-2-Iodo-3-Methyl-5-Nitrobenzene
CAS No.	1160573-59-0
Molecular Formula	C7H5BrINO2
Molecular Weight	341.93 g/mol
Synonyms	2-Bromo-1-Iodo-3-Methyl-5-Nitrobenzene; 3-Methyl-5-Nitro-1,2-Dihalobenzene; Benzene, 1-bromo-2-iodo-3-methyl-5-nitro-; 5-Nitro-1-bromo-2-iodo-3-methylbenzene; 1-Bromo-2-iodo-3-methyl-5-nitro-benzene; 2-Iodo-1-bromo-3-methyl-5-nitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Iodo-3-Methyl-5-Nitrobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.