Description

1-Bromo-4-Iodo-2,3-Dimethylbenzene is a high-purity, halogenated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its dual halogen functionality, which provides distinct reactive sites for sequential cross-coupling reactions and structural elaboration. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogen-substituted aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromo and iodo groups allow for versatile derivatization.
• Material Science Research: Serves as a monomer or building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings, enabling carbon-carbon bond formation.
• Chemical Library Development: Employed in medicinal chemistry for the parallel synthesis of diverse compound libraries to explore structure-activity relationships (SAR).
• Ligand and Catalyst Preparation: Used to synthesize sophisticated ligands for catalysis or as a scaffold for catalyst development.

Basic Information

Product Name	1-Bromo-4-Iodo-2,3-Dimethylbenzene
CAS No.	1160573-43-2
Molecular Formula	C8H8BrI
Molecular Weight	311.96 g/mol
Synonyms	2,3-Dimethyl-1-bromo-4-iodobenzene; 4-Bromo-1-iodo-2,3-dimethylbenzene; 1-Bromo-4-iodo-2,3-dimethylbenzol; 2,3-Dimethyl-4-iodobromobenzene; Benzene, 1-bromo-4-iodo-2,3-dimethyl-; (2,3-Dimethylphenyl)bromoiodide (ambiguous); Br, I-Dimethylbenzene derivative
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Iodo-2,3-Dimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.