Description

1-(4-Methyl-2-Nitrophenyl)-5-Oxopyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrrolidinone-carboxylic acid structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic frameworks due to its reactive carboxylic acid and lactam functional groups.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for method development and structure-activity relationship (SAR) studies.
• API Process Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients during clinical trial material preparation.

Basic Information

Product Name	1-(4-Methyl-2-Nitrophenyl)-5-Oxopyrrolidine-3-Carboxylic Acid
CAS No.	1160264-10-7
Molecular Formula	C12H12N2O5
Molecular Weight	264.24 g/mol
Synonyms	5-Oxo-1-(4-methyl-2-nitrophenyl)pyrrolidine-3-carboxylic acid; 1-(4-Methyl-2-nitrophenyl)-5-oxo-3-pyrrolidinecarboxylic acid; 3-Pyrrolidinecarboxylic acid, 1-(4-methyl-2-nitrophenyl)-5-oxo-; 5-Oxopyrrolidine-3-carboxylic acid, 1-(4-methyl-2-nitrophenyl)- derivative; 1160264-10-7; 1-(4-Methyl-2-nitro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Methyl-2-Nitrophenyl)-5-Oxopyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.