Description

Potassium 2-Cyanoethyltrifluoroborate is a versatile organoboron reagent, specifically a potassium trifluoroborate salt, with the CAS number 1159919-79-5. This compound is valued for its enhanced stability and handling properties compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and the cyanoethyl moiety, enabling the synthesis of complex intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing functionalized ethyl chains.
• Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific nitrile-containing side chains.
• Materials Science & OLED Research: Serves as a precursor for organic electronic materials, where the cyano group can influence charge transport properties.
• Peptide Modification & Bioconjugation: Utilized for the site-specific functionalization of peptides and proteins via stable boron-based linkages.
• Ligand Synthesis for Catalysis: Acts as a building block for creating sophisticated phosphine or nitrogen-based ligands used in homogeneous catalysis.

Basic Information

Product Name	Potassium 2-Cyanoethyltrifluoroborate
CAS No.	1159919-79-5
Molecular Formula	C3H4BF3KN
Molecular Weight	164.98 g/mol
Synonyms	Potassium (2-Cyanoethyl)trifluoroborate; 2-Cyanoethyltrifluoroborate Potassium Salt; Potassium 3-Cyanopropyltrifluoroborate; Potassium Trifluoro(2-cyanoethyl)borate; (2-Cyanoethyl)potassium Trifluoroborane; K-2-Cyanoethyltrifluoroborate; K[C2H4CN]BF3; Potassium β-Cyanoethyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 2-Cyanoethyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Potentiometric Titration)	≥ 97%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, methanol, DMF; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.