Description

1H-Pyrazolo[4,3-C]Pyridine, 4-Bromo- is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its unique heterocyclic structure.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: A versatile scaffold for generating diverse compound libraries in high-throughput screening campaigns.

Basic Information

Product Name	1H-Pyrazolo[4,3-C]Pyridine, 4-Bromo-
CAS No.	1159829-63-6
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	4-Bromo-1H-pyrazolo[4,3-c]pyridine; 4-Bromo-1H-pyrazolo[4,3-c]pyridine; 4-Bromopyrazolo[4,3-c]pyridine; 1H-Pyrazolo[4,3-c]pyridine, 4-bromo-; 1159829-63-6; 4-Bromo-1H-pyrazolo[4,3-c]pyridin; 4-Bromo-1H-pyrazolo[4,3-c]pyridine (ACI)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-C]Pyridine, 4-Bromo- is manufactured under strict quality management systems. We provide material with typical purity grades suitable for research and development, supported by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and LC-MS are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Typical)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.