Description

1-(2-Fluoro-5-Iodophenyl)Ethan-1-One is a high-purity fluorinated and iodinated aromatic ketone, serving as a critical advanced pharmaceutical intermediate. Its unique halogenated structure makes it an essential building block for synthesizing complex molecules in medicinal chemistry. This compound is primarily required by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated phenyl ring for bioactivity.
• Material Science Research: Acts as a precursor for specialty polymers and liquid crystals that require halogenated aromatic components.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and functional group transformations due to the reactive iodine and ketone moieties.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Fluoro-5-Iodophenyl)Ethan-1-One
CAS No.	1159512-66-9
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	2'-Fluoro-5'-iodoacetophenone; 1-Acetyl-2-fluoro-5-iodobenzene; 2-Fluoro-5-iodoacetophenone; Ethanone, 1-(2-fluoro-5-iodophenyl)-; 5-Iodo-2-fluoroacetophenone; (2-Fluoro-5-iodophenyl)methyl ketone; 1-(2-Fluoro-5-iodophenyl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-Iodophenyl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.