Description

2-(3-Bromo-2,4-Difluorophenyl)Acetonitrile is a high-value, multi-functional aromatic nitrile building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive bromo and cyano groups on a difluorinated aromatic core. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(3-Bromo-2,4-Difluorophenyl)Acetonitrile
CAS No.	1159186-98-7
Molecular Formula	C8H4BrF2N
Molecular Weight	232.03 g/mol
Synonyms	(3-Bromo-2,4-difluorophenyl)acetonitrile; 2-(3-Bromo-2,4-difluorophenyl)ethanenitrile; 3-Bromo-2,4-difluorobenzyl cyanide; α-Cyano-3-bromo-2,4-difluorotoluene; 1159186-98-7; 2,4-Difluoro-3-bromobenzyl cyanide
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-2,4-Difluorophenyl)Acetonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.