Description

1-(Phenylsulfonyl)Indole-2-Boronic Acid Mida Ester, 1-(Phenylsulfonyl)Indole-2-Boronic Acid, Methyliminodiacetic Acid Anhydride is a sophisticated, multi-functional chemical building block designed for advanced synthetic applications. This compound is valued for its role as a protected boronic acid derivative, offering enhanced stability and controlled reactivity in cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic acid ester reagent for the formation of carbon-carbon bonds in complex molecule assembly.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with indole core structures.
• Material Science: Potential precursor for creating organic electronic materials and functional polymers.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry research programs.
• Process Chemistry: Employed in route scouting and optimization for scalable manufacturing of fine chemicals.

Basic Information

Product Name	1-(Phenylsulfonyl)Indole-2-Boronic Acid Mida Ester, 1-(Phenylsulfonyl)Indole-2-Boronic Acid, Methyliminodiacetic Acid Anhydride
CAS No.	1158984-95-2
Molecular Formula	C₁₉H₁₇BN₂O₆S
Molecular Weight	412.22 g/mol
Synonyms	1-(Benzenesulfonyl)-1H-indole-2-boronic acid MIDA ester; N-Methyliminodiacetic acid (1-(Phenylsulfonyl)indol-2-yl)boronate; 1-(Phenylsulfonyl)indole-2-boronic acid N-methyliminodiacetic acid ester; MIDA Boronate Ester of 1-(Phenylsulfonyl)indole-2-boronic acid; 1H-Indole-2-boronic acid, 1-(phenylsulfonyl)-, 1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetate ester; Boronic acid, B-[1-(phenylsulfonyl)-1H-indol-2-yl]-, (2,2'-(methylimino)diacetate); Protected Indole-2-Boronic Acid Ester.
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Indole-2-Boronic Acid Mida Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.