Description

5-(4-Fluorophenyl)Picolinaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a picolinaldehyde and a fluorophenyl moiety, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or affinity probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-(4-Fluorophenyl)Picolinaldehyde
CAS No.	1158763-46-2
Molecular Formula	C₁₂H₈FNO
Molecular Weight	201.20 g/mol
Synonyms	5-(4-Fluorophenyl)pyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 5-(4-fluorophenyl)-; 5-(p-Fluorophenyl)picolinaldehyde; 5-(4-Fluorophenyl)-2-pyridinecarboxaldehyde; 5-(4-Fluorophenyl)-2-formylpyridine; 2-Formyl-5-(4-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Picolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures batch-to-batch consistency, meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.