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(4-Bromo-2-Chlorophenyl)(4-Chlorophenyl)Methanone CAS NO 1157395-92-0
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CAS No.:1157395-92-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(4-Bromo-2-Chlorophenyl)(4-Chlorophenyl)Methanone is a high-purity diaryl ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated aromatic structure, which provides specific reactivity and steric properties essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
- Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
- Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, halogenated core.
- Chemical Biology Probes: Serves as a scaffold for creating molecular probes and inhibitors for studying enzyme function and biological pathways.
- Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated intermediates.
Basic Information
| Product Name | (4-Bromo-2-Chlorophenyl)(4-Chlorophenyl)Methanone |
| CAS No. | 1157395-92-0 |
| Molecular Formula | C13H7BrCl2O |
| Molecular Weight | 330.00 g/mol |
| Synonyms | 4-Bromo-2,4'-Dichlorobenzophenone; 1-Bromo-4-(4-Chlorobenzoyl)-2-Chlorobenzene; (4-Bromo-2-chlorophenyl)(4-chlorophenyl)methanone; 4'-Chloro-4-bromo-2-chlorobenzophenone; 2-Chloro-4-bromo-4'-chlorobenzophenone; Benzophenone, 4-bromo-2,4'-dichloro-; Methanone, (4-bromo-2-chlorophenyl)(4-chlorophenyl)- |
| EINECS | Contact for details |
Quality Control
Our (4-Bromo-2-Chlorophenyl)(4-Chlorophenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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