Description

4-(4-Bromophenoxy)-1-Nitro-2-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic compound featuring bromophenoxy, nitro, and trifluoromethyl substituents, making it a versatile and reactive synthetic intermediate. Its unique structure provides a critical building block for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology, leveraging the electron-withdrawing properties of the nitro and trifluoromethyl groups.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the bromine atom offers a site for further functionalization via cross-coupling reactions.
• Liquid Crystal & OLED Material Research: Acts as a core or side-chain component in the design of organic semiconductors, liquid crystal displays (LCDs), and organic light-emitting diodes (OLEDs) due to its rigid, substituted benzene structure.
• Polymer Modification: Employed to introduce specific functional groups into polymer backbones, enhancing properties like thermal stability, chemical resistance, or optical characteristics for high-performance plastics and coatings.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions such as Suzuki, Heck, and Sonogashira couplings, enabling the construction of complex biaryl systems.
• Chemical Research & Development: Provides a versatile scaffold for exploring new reaction pathways and synthesizing libraries of compounds for high-throughput screening in various chemical and biological applications.

Basic Information

Product Name	4-(4-Bromophenoxy)-1-Nitro-2-(Trifluoromethyl)Benzene
CAS No.	1156314-30-5
Molecular Formula	C13H7BrF3NO3
Molecular Weight	362.10 g/mol
Synonyms	1-Nitro-4-(4-bromophenoxy)-2-(trifluoromethyl)benzene; 4-(4-Bromophenoxy)-α,α,α-trifluoro-2-nitrotoluene; 2-Nitro-α,α,α-trifluoro-4-(p-bromophenoxy)toluene; 4-(p-Bromophenoxy)-1-nitro-2-(trifluoromethyl)benzene; 1-Nitro-2-trifluoromethyl-4-(4-bromophenoxy)benzene; Benzene, 1-nitro-4-(4-bromophenoxy)-2-(trifluoromethyl)-; [1156314-30-5]
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Bromophenoxy)-1-Nitro-2-(Trifluoromethyl)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.