Description

3-Fluoro-4-Hydroxybenzamide is a high-purity fluorinated benzamide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a versatile intermediate for creating compounds with tailored biological and physical properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in kinase inhibitor and CNS-active molecule libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display and lighting materials.
• Biochemical Research: Employed as a standard or probe in metabolic pathway studies and enzyme inhibition assays.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorine and amide groups into specialty polymers.
• Organic Synthesis Building Block: Utilized in Suzuki, Buchwald-Hartwig, and other cross-coupling reactions to construct complex aromatic systems.

Basic Information

Product Name	3-Fluoro-4-Hydroxybenzamide
CAS No.	1155354-10-1
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	4-Hydroxy-3-fluorobenzamide; 3-Fluoro-4-hydroxybenzoic acid amide; 3-Fluoro-4-hydroxy-benzamide; 3-Fluoro-4-hydroxybenzenecarboxamide; 3-Fluoro-4-hydroxybenzamide (CAS 1155354-10-1); 3-Fluoro-4-hydroxy benzamide; 3-Fluoro-4-hydroxy-benzamide
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Hydroxybenzamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and other high-value applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.