Description

2-(1-Chloronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl chlorides and various boronic acids/esters, crucial in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex polycyclic aromatic systems.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific chloronaphthalene motifs.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for synthesizing electron-transport or host materials containing naphthalene cores.
• Ligand and Catalyst Development: Useful for preparing specialized ligands or metal-organic frameworks (MOFs) with tailored properties.
• Polymer and Material Science: Serves as a monomer or functionalization agent for creating polymers with specific aromatic characteristics.

Basic Information

Product Name	2-(1-Chloronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1154740-95-0
Molecular Formula	C16H19BClO2
Molecular Weight	298.59 g/mol
Synonyms	1-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 2-(1-Chloronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Chloro-2-naphthaleneboronic acid pinacol ester; (1-Chloro-2-naphthyl)boronic acid pinacol ester; 2-(1-Chloro-2-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Chloro-2-(pinacolboronato)naphthalene; 1154740-95-0; 2-(1-Chloro-naphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(1-Chloronaphthalen-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.